The Association between Vitamin K2 Intake and Glucose Homeostasis in Individuals with and without Chronic Kidney Disease

Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder worldwide. Subclinical micronutrient deficiencies have been found to contribute to glucose intolerance and insulin resistance. Vitamin K₂, in particular, possesses extrahepatic activities that may influence glucose metabolism. Individuals with chronic kidney disease (CKD) have poorer vitamin K status as well as impaired insulin sensitivity and glucose tolerance. However, whether or not the poorer metabolic outcome correlates with intakes of vitamin K₂ is unclear. The objective of this study was to investigate whether the intake of vitamin K₂ is associated with glucose tolerance and key factors determining glucose tolerance.

Materials Available

• Abstract

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Project Type(s): Master's Thesis

Author(s): Hsin-Hui (Katty) Tseng

Program(s): Master of Science

Year: 2016

Adviser(s):

• Mario Kratz