Effects of differentially sweetened beverages on hepatic and adipose tissue de novo lipogenesis in healthy young adults

Added sugars from sweetened beverages contribute a substantial number of calories to the American diet with numerous associated negative health effects. There is a need to evaluate the different effects of fructose, glucose, and aspartame on healthy young adult metabolism to better understand the etiology of obesity and obesity-associated diseases. This study aims to evaluate differences in de novo lipogenesis in adipose tissue versus the liver when subjects consume differentially sweetened beverages, based on research in rodent models suggesting that the balance of hepatic vs. adipose tissue lipogenesis has substantial effects on energy and glucose homeostasis.

Materials Available

• Abstract

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Project Type(s): Master's Thesis

Author(s): Sarah Shimer

Program(s): Master of Public Health

Year: 2012

Adviser(s):

• Mario Kratz