Evaluation of Select Food Additive Exposures in Children with Crohn’s Disease

Crohn’s Disease (CD) is a chronic, debilitating inflammatory bowel disease and recent research has revealed the possibility that environmental exposures such as diet may play a role in CD etiology and disease activity. Several food additives (e.g. carboxymethylcellulose, carrageenan, maltodextrin) have been shown to cause intestinal inflammation, mucosal barrier alterations, and microbiome dysbiosis in animal models, therefore it has been hypothesized that these additives may be associated with disease activity in children with CD. This project evaluated food additive exposure in children with CD in an effort to understand additive intake among this population and to establish a methodology for future studies.

Materials Available

• Abstract

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Project Type(s): Master's Thesis

Author(s): C. Kaulani Swan

Program(s): Master of Science, RDN Training

Year: 2016

Adviser(s):

• Johanna W. Lampe